How to do partial page postbacks WITHOUT AJAX UPDATE PANEL in ASP.NET?

With out using Update Panel its not possible in asp.net web form  besiccelly ASP.NET AJAX uses 'normal' AJAX to 'ajax-ify' it's pages and achieve partial-updates...and in doing so, it trades & manages view-state MULTIPLE times throughout a single call. This is WHY it is called a 'partial-postback'. Subsequently, this is also why they originally described the UpdatePanel as a means to make your pages 'ajaxy' (because it is not the same thing as using AJAX).but if you want to do that so try to use webmethods with json or jquery

For more refer:- http://www.aspsnippets.com/Articles/Insert-Update-Data-to-Database-with-jQuery-AJAX-and-WebMethod-in-ASPNet.aspx